They are far easier on multiple targets in the dark. Transitioning from one target to another to another is very simple and very fluid. There's no added time to settle down on each target -- just bang and go.
On moving targets, especially on moving targets in the dark, they are faster and easier than any other system. Singles or multiples, if the target is moving, it's just flat out easier with a laser. Again, no comparison is possible. Very few people have had opportunity to shoot movers in the dark, but take my word on this one: if you want to hit something that is moving, and if lighting conditions are less than optimal, the laser is absolutely the way to go.
A story from a local gun shop: The homeowner heard some noise in the house and got up to investigate, taking his laser-equipped handgun with him. He saw something ominous and, directing the laser dot of his handgun at the human shape, cut loose with several rounds.
After the commotion died down and the lights were turned on, his wife was less than amused to find several holes in the fur coat she had hung up on a coat rack.
Personally, I don't understand how any sight can compensate for lack of practice firing the weapon. I will agree that a certain kind of sight can improve shooting: with my older eyes, an aperture sight helps me to shoot better than normal iron sights and I do even better with an optical sight, be it red dot or scope. But the use of an improved sight still does not compensate for proper hold, or technique, or just plain being used to firing the weapon.
Secondly, as the little story illustrates, using a laser sight can never be a substitute for one of the most basic and important gun safety practices: that of knowing your target. When thinking of discharging my weapon inside my home, I can think of nothing more important than being sure of my target and being sure that my shooting isn't going to endanger a loved one. If this rule is to be disregarded, what's the difference between my promiscuous shooting and letting the goon do whatever? The point is protecting my loved ones and myself, and if my shooting harms innocent people, then something is dreadfully wrong with the whole idea.
The laser is only going to shine a small dot on a surface. If the owner of that surface is not known, there's a potential for a big problem. If what is behind that surface is a thin wall between the weapon and a sleeping loved one, there is a big problem. Whatever laser sights can do in the dark, they are intended to aim the weapon, not illuminate the target for identification.